Monthly Archives: November 2012

Network based approach to study DNA-DNA contacts published in Nucleic Acids Research

In this paper, we present a general statistical framework that is widely applicable to the analysis of genomic contact maps, irrespective of the data acquisition and normalization processes. Within this framework DNA–DNA contact data are represented as a complex network … Continue reading

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Strategies to control functional and non-functional aggregation published in Cell Reports

Growing evidence suggests that aggregation-prone proteins are both harmful and functional for a cell. How do cellular systems balance the detrimental and beneficial effect of protein aggregation? In this work, we reveal that aggregation-prone proteins are subject to differential transcriptional, … Continue reading

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